On route to the airport, nineteen-year-old Katelin Akens makes an unexpected stop at a Virginia shopping mall...and vanishes. Police investigate her loved ones at length and start to suspect that someone close to Katelin may know more than they're saying.

Deanne Hastings, a 35-year-old Spokane mom, leaves a note that she's running to the store, but she never returns. As detectives uncover more information about Deanne's actions leading up to her disappearance, a slew of troubling theories emerge.

In the middle of the night at his home in Clearwater, Florida, eight-year-old Zachary Bernhardt disappears. His mother was taking a quick late night dip in their apartment's pool, then went to check on him but found that he wasn't in his bed. There is no sign of a break in or struggle, and suspicions swirl around the single mother, who denies any involvement in her son's disappearance and ends up moving away. But when another boy goes missing from the area, new theories emerge as the quiet beach town is gripped by fear. After sixteen years of not knowing what happened, Zachary's family and local law enforcement continues to search for answers.

Ashley Summers is a fun-loving 14-year-old. When she vanishes on July 4th, her family is at a loss. The mystery deepens when the FBI connects her case to two other young women missing from her neighborhood.Ten years later, there's still no answer.

Eric Lee Franks 38 from Saginaw Michigan moved to Ohio in 2013 to meet the teenage daughter he didn't know about, 6 months later his mother in Michigan reported him missing.

Logan Schiendelman vanishes, and authorities find his car abandoned. Multiple tips claim seeing Logan, but searches turn up nothing. With no evidence of foul play, questions surface and police are forced to examine his family's controversial past.

A date night in Philadelphia becomes deeply disturbing when a couple disappears. Their families unite to find them, but as desperation grows, finger pointing puts them at odds. Soon, the FBI takes over the investigation that is riddled with speculation.

19-year-old Angel Garcia disappears after riding his dirt bike around Hartford CT. Friends say Angel was chased by a mysterious SUV before he disappeared. Months Later, a possible sighting in a convenience store 15 miles from home. Could it be Angel?

20-year old Bear Diaz has diabetes, leaving him weak and vulnerable. When he vanishes in the night with his TV, backpack and cash, investigators must consider foul play. Then Skylar Tosic disappears, leaving people wondering if the cases are linked.

After a night at home watching movies, 18-year-old Zoe Campos cannot be found by her family the next morning. As investigators pore through the teen's Facebook account, they discover she did not turn in early as her loved ones originally thought.

When 15-yr-old Kayla Berg isn't home after a night out, her loved ones believe she's staying with friends. But when six days pass and the aspiring gymnast is missing, the details of her last known whereabouts raise suspicion in a close-knit town.

While on a Caribbean cruise, 23-year-old Amy Bradley vanishes from her family's cabin and is never seen again. Over a decades-long struggle, her family embarks on countless grueling searches, stopping at nothing, they say, to find their beloved Amy.

Stephanie Crane, aged 9, walks home from the local bowling alley-but never arrives. Early leads go nowhere. For years authorities don't find her or make an arrest. Now, they hope that advances in evidence testing may finally solve the mystery.

When Sage Smith, a transgender teen in Charlottesville, Virginia goes missing, police identify a suspect. But the investigation turns up evidence that forces detectives to look closer into Sage's inner circle to see if there are answers.

Nineteen-year-old Tyarra Williams vanishes from the parking lot of her Greensboro, N.C., apartment complex. When tips suggest that Tyarra may have fallen prey to human trafficking, her grandfather embarks on a cross country search for answers.

Mother of three, Holly Cantrell, is seen on security video exiting the Oklahoma hospital where she works but never returns home. Police learn Holly was keeping secrets, and her loved ones wonder if those had anything to do with her disappearance.